KCNJ16
Gene Information
- Official Symbol: KCNJ16
- Official Name: potassium inwardly rectifying channel subfamily J member 16
- Aliases and Previous Symbols: N/A
- Entrez ID: 3773
- UniProt: Q9NPI9
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ16 may be involved in the regulation of fluid and pH balance. In the kidney, together with KCNJ10, mediates basolateral K(+) recycling in distal tubules; this process is critical for Na(+) reabsorption at the tubules (PubMed:24561201). {ECO:0000305|PubMed:24561201}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 8038
- Expression level (log2 read counts): 1.39
KCNJ16 Expression in NALM6 Cells: 1.39
