Entrez Summary: This gene encodes a mitochondrial outer membrane protein. It has a potential role in tumorigenesis, which may result from negative regulation of the p53 tumor suppressor gene. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Aug 2011].
UniProt Summary: N/A
Pfam DomainsGO Terms
Pfam Domains
LETM1
GO Terms
ribosome binding
mitochondrial outer membrane
mitochondrial inner membrane
mitochondrion
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)