LYRM4
Gene Information
- Official Symbol: LYRM4
- Official Name: LYR motif containing 4
- Aliases and Previous Symbols: N/A
- Entrez ID: 57128
- UniProt: Q9HD34
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: The protein encoded by this gene is found in both mitochondria and the nucleus, where it binds cysteine desulfurase and helps free inorganic sulfur for Fe/S clusters. Disruption of this gene negatively impacts mitochondrial and cytosolic iron homeostasis. [provided by RefSeq, Sep 2016].
- UniProt Summary: Required for nuclear and mitochondrial iron-sulfur protein biosynthesis. {ECO:0000269|PubMed:17331979, ECO:0000269|PubMed:19454487}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 1898
- Expression level (log2 read counts): 5.37
LYRM4 Expression in NALM6 Cells: 5.37
