Pfam Domains GO Terms
| regulation of chromatin disassembly |
| deoxyribonuclease activity |
| regulation of chromatin assembly or disassembly |
| mitochondrion transport along microtubule |
| establishment of mitochondrion localization, microtubule-mediated |
| establishment of mitochondrion localization |
| regulation of microtubule depolymerization |
| microtubule associated complex |
| beta-tubulin binding |
| mitochondrion localization |
| tubulin binding |
| organelle transport along microtubule |
| regulation of microtubule polymerization or depolymerization |
| regulation of protein depolymerization |
| microtubule bundle formation |
| cell projection |
| dendrite development |
| regulation of protein complex disassembly |
| spindle |
| transport along microtubule |
| cytoskeleton-dependent intracellular transport |
| microtubule-based transport |
| regulation of microtubule cytoskeleton organization |
| regulation of chromatin organization |
| actin filament binding |
| regulation of microtubule-based process |
| microtubule binding |
| autophagy |
| process utilizing autophagic mechanism |
| actin binding |
| synapse |
| microtubule-based movement |
| microtubule |
| regulation of chromosome organization |
| regulation of supramolecular fiber organization |
| establishment of organelle localization |
| neuronal cell body |
| axonogenesis |
| axon development |
| dendrite |
| cell morphogenesis involved in neuron differentiation |
| microtubule cytoskeleton organization |
| neuron projection morphogenesis |
| plasma membrane bounded cell projection morphogenesis |
| cell projection morphogenesis |
| cell part morphogenesis |
| regulation of cytoskeleton organization |
| cell junction |
| cell morphogenesis involved in differentiation |
| organelle localization |
| neuron projection development |
| microtubule-based process |
| perinuclear region of cytoplasm |
| cell morphogenesis |
| brain development |
| DNA metabolic process |
| head development |
| neuron development |
| cellular component morphogenesis |
| nucleolus |
| apoptotic process |
| central nervous system development |
| neuron differentiation |
| programmed cell death |
| identical protein binding |
| cell death |
| cytoskeleton organization |
| plasma membrane bounded cell projection organization |
| cell projection organization |
| regulation of organelle organization |
| DNA binding |
| intracellular transport |
| generation of neurons |
| movement of cell or subcellular component |
| neurogenesis |
| cell development |
| cellular catabolic process |
| establishment of localization in cell |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution