Pfam Domains GO Terms
| MARVEL |
| protein localization to cell junction |
| mitogen-activated protein kinase kinase kinase binding |
| bicellular tight junction assembly |
| negative regulation of JNK cascade |
| tight junction assembly |
| tight junction organization |
| apical junction assembly |
| negative regulation of stress-activated MAPK cascade |
| negative regulation of stress-activated protein kinase signaling cascade |
| negative regulation of epithelial cell migration |
| response to osmotic stress |
| cell-cell junction assembly |
| bicellular tight junction |
| negative regulation of epithelial cell proliferation |
| cell-cell junction organization |
| negative regulation of MAPK cascade |
| cell junction assembly |
| regulation of JNK cascade |
| cell junction organization |
| regulation of epithelial cell migration |
| regulation of stress-activated MAPK cascade |
| regulation of stress-activated protein kinase signaling cascade |
| cytoplasmic vesicle |
| negative regulation of cell migration |
| negative regulation of cell motility |
| negative regulation of cellular component movement |
| negative regulation of locomotion |
| regulation of epithelial cell proliferation |
| negative regulation of protein phosphorylation |
| negative regulation of phosphorylation |
| negative regulation of intracellular signal transduction |
| negative regulation of phosphate metabolic process |
| negative regulation of phosphorus metabolic process |
| negative regulation of protein modification process |
| negative regulation of cell population proliferation |
| regulation of cellular response to stress |
| regulation of MAPK cascade |
| regulation of cell migration |
| regulation of cell motility |
| regulation of locomotion |
| regulation of cellular component movement |
| negative regulation of cellular protein metabolic process |
| negative regulation of protein metabolic process |
| response to abiotic stimulus |
| negative regulation of multicellular organismal process |
| negative regulation of signal transduction |
| negative regulation of cell communication |
| negative regulation of signaling |
| regulation of protein phosphorylation |
| regulation of response to stress |
| regulation of phosphorylation |
| regulation of cell population proliferation |
| negative regulation of response to stimulus |
| regulation of phosphate metabolic process |
| regulation of phosphorus metabolic process |
| regulation of intracellular signal transduction |
| regulation of protein modification process |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution