MAST2
Gene Information
- Official Symbol: MAST2
- Official Name: microtubule associated serine/threonine kinase 2
- Aliases and Previous Symbols: N/A
- Entrez ID: 23139
- UniProt: Q6P0Q8
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins. Functions in a multi-protein complex in spermatid maturation. Regulates lipopolysaccharide-induced IL-12 synthesis in macrophages by forming a complex with TRAF6, resulting in the inhibition of TRAF6 NF-kappa-B activation (By similarity). {ECO:0000250}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 11704
- Expression level (log2 read counts): 5.37
MAST2 Expression in NALM6 Cells: 5.37
