UniProt Summary: Functions in replication-dependent translation of histone mRNAs which differ from other eukaryotic mRNAs in that they do not end with a poly-A tail but a stem-loop. May participate in circularizing those mRNAs specifically enhancing their translation. {ECO:0000269|PubMed:18025107}.
Pfam DomainsGO Terms
Pfam Domains
MIF4G
GO Terms
translation activator activity
regulation of translational initiation
positive regulation of translation
positive regulation of cellular amide metabolic process
protein C-terminus binding
regulation of translation
regulation of cellular amide metabolic process
posttranscriptional regulation of gene expression
nucleolus
identical protein binding
RNA binding
positive regulation of cellular protein metabolic process
positive regulation of protein metabolic process
positive regulation of macromolecule biosynthetic process
positive regulation of cellular biosynthetic process
positive regulation of gene expression
positive regulation of biosynthetic process
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)