MOXD1
Gene Information
- Official Symbol: MOXD1
- Official Name: monooxygenase DBH like 1
- Aliases and Previous Symbols: N/A
- Entrez ID: 26002
- UniProt: Q6UVY6
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| Cu2 monooxygen |
| DOMON |
| Cu2 monoox C |
GO Terms
| dopamine beta-monooxygenase activity |
| octopamine metabolic process |
| octopamine biosynthetic process |
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen |
| norepinephrine biosynthetic process |
| ethanolamine-containing compound metabolic process |
| dopamine catabolic process |
| catechol-containing compound catabolic process |
| catecholamine catabolic process |
| phenol-containing compound catabolic process |
| norepinephrine metabolic process |
| catechol-containing compound biosynthetic process |
| catecholamine biosynthetic process |
| cellular biogenic amine biosynthetic process |
| amine biosynthetic process |
| dopamine metabolic process |
| phenol-containing compound biosynthetic process |
| neurotransmitter biosynthetic process |
| catechol-containing compound metabolic process |
| catecholamine metabolic process |
| copper ion binding |
| cellular biogenic amine metabolic process |
| cellular amine metabolic process |
| amine metabolic process |
| organic hydroxy compound catabolic process |
| phenol-containing compound metabolic process |
| neurotransmitter metabolic process |
| secretory granule membrane |
| alcohol biosynthetic process |
| drug catabolic process |
| organic hydroxy compound biosynthetic process |
| ammonium ion metabolic process |
| alcohol metabolic process |
| regulation of neurotransmitter levels |
| aromatic compound catabolic process |
| organic hydroxy compound metabolic process |
| organic cyclic compound catabolic process |
| drug metabolic process |
| small molecule biosynthetic process |
| endoplasmic reticulum membrane |
| oxidation-reduction process |
| organonitrogen compound catabolic process |
| aromatic compound biosynthetic process |
| organic cyclic compound biosynthetic process |
| organonitrogen compound biosynthetic process |
| extracellular space |
| cellular nitrogen compound biosynthetic process |
| small molecule metabolic process |
| organic substance catabolic process |
| cellular catabolic process |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
| Screen | Score |
|---|---|
| BI-2536 0.0042μM R03 exp95 | -1.77 |
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 14263
- Expression level (log2 read counts): -3.13
Expression Distribution
MOXD1 Expression in NALM6 Cells: -3.13
