UniProt Summary: May serve as an important signal transducer for a novel upstream stimuli in controlling cell proliferation. Weakly activates the MAP kinase pathway. {ECO:0000269|PubMed:16630891}.
Pfam DomainsGO Terms
Pfam Domains
Ras
GTP EFTU
Miro
Arf
GO Terms
GTP-dependent protein binding
GDP binding
response to leukemia inhibitory factor
cellular response to leukemia inhibitory factor
Ras protein signal transduction
muscle organ development
small GTPase mediated signal transduction
GTPase activity
GTP binding
muscle structure development
actin cytoskeleton organization
actin filament-based process
cellular response to cytokine stimulus
response to cytokine
cytoskeleton organization
intracellular signal transduction
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)