Pfam Domains GO Terms
| Filament |
| Filament head |
| intermediate filament polymerization or depolymerization |
| presynaptic intermediate filament cytoskeleton |
| response to acrylamide |
| postsynaptic intermediate filament cytoskeleton |
| neurofilament bundle assembly |
| postsynaptic intermediate filament cytoskeleton organization |
| structural constituent of postsynaptic intermediate filament cytoskeleton |
| regulation of axon diameter |
| response to sodium arsenite |
| peripheral nervous system axon regeneration |
| intermediate filament bundle assembly |
| neurofilament |
| neurofilament cytoskeleton organization |
| cholinergic synapse |
| synapse maturation |
| axonal transport of mitochondrion |
| response to herbicide |
| regulation of cell projection size |
| postsynaptic cytoskeleton organization |
| phospholipase binding |
| response to insecticide |
| retrograde axonal transport |
| response to salt |
| response to corticosterone |
| mitochondrion transport along microtubule |
| establishment of mitochondrion localization, microtubule-mediated |
| axon regeneration |
| intermediate filament organization |
| establishment of mitochondrion localization |
| neuron projection regeneration |
| response to arsenic-containing substance |
| response to mineralocorticoid |
| regulation of NMDA receptor activity |
| anterograde axonal transport |
| mitochondrion localization |
| response to axon injury |
| intermediate filament cytoskeleton organization |
| intermediate filament-based process |
| neuromuscular process controlling balance |
| axonal transport |
| axon cytoplasm |
| regulation of glutamate receptor signaling pathway |
| axo-dendritic transport |
| regulation of neurotransmitter receptor activity |
| neuromuscular junction |
| protein binding, bridging |
| organelle transport along microtubule |
| hippocampus development |
| Schaffer collateral - CA1 synapse |
| positive regulation of axonogenesis |
| protein polymerization |
| postsynapse organization |
| response to antineoplastic agent |
| structural constituent of cytoskeleton |
| spinal cord development |
| neuromuscular process |
| limbic system development |
| cerebral cortex development |
| growth cone |
| response to glucocorticoid |
| negative regulation of neuron apoptotic process |
| positive regulation of cell morphogenesis involved in differentiation |
| transport along microtubule |
| regeneration |
| response to corticosteroid |
| regulation of cation channel activity |
| regulation of signaling receptor activity |
| pallium development |
| cytoskeleton-dependent intracellular transport |
| microtubule-based transport |
| regulation of axonogenesis |
| protein C-terminus binding |
| response to ketone |
| negative regulation of neuron death |
| regulation of neuron apoptotic process |
| response to alcohol |
| developmental maturation |
| protein domain specific binding |
| regulation of ion transmembrane transporter activity |
| telencephalon development |
| regulation of transmembrane transporter activity |
| synapse organization |
| microtubule-based movement |
| regulation of transporter activity |
| positive regulation of neuron projection development |
| axon |
| response to antibiotic |
| regulation of cell morphogenesis involved in differentiation |
| regulation of neuron death |
| response to steroid hormone |
| regulation of cation transmembrane transport |
| establishment of organelle localization |
| positive regulation of neuron differentiation |
| MAPK cascade |
| regulation of cellular component size |
| positive regulation of cell projection organization |
| forebrain development |
| response to peptide hormone |
| signal transduction by protein phosphorylation |
| axon development |
| supramolecular fiber organization |
| positive regulation of neurogenesis |
| response to peptide |
| microtubule cytoskeleton organization |
| regulation of ion transmembrane transport |
| neuron projection morphogenesis |
| plasma membrane bounded cell projection morphogenesis |
| protein heterodimerization activity |
| regulation of cell morphogenesis |
| cell projection morphogenesis |
| regulation of neuron projection development |
| response to toxic substance |
| cell part morphogenesis |
| regulation of anatomical structure size |
| response to inorganic substance |
| positive regulation of nervous system development |
| positive regulation of cell development |
| regulation of transmembrane transport |
| response to wounding |
| organelle localization |
| regulation of neuron differentiation |
| neuron projection development |
| microtubule-based process |
| regulation of plasma membrane bounded cell projection organization |
| regulation of ion transport |
| regulation of cell projection organization |
| cell morphogenesis |
| brain development |
| head development |
| neuron development |
| regulation of neurogenesis |
| cellular component morphogenesis |
| cellular protein-containing complex assembly |
| response to lipid |
| negative regulation of apoptotic process |
| negative regulation of programmed cell death |
| response to hormone |
| response to organic cyclic compound |
| regulation of nervous system development |
| regulation of cell development |
| positive regulation of cell differentiation |
| protein phosphorylation |
| central nervous system development |
| negative regulation of cell death |
| response to organonitrogen compound |
| neuron differentiation |
| response to drug |
| regulation of anatomical structure morphogenesis |
| identical protein binding |
| response to nitrogen compound |
| cytoskeleton organization |
| plasma membrane bounded cell projection organization |
| cell projection organization |
| positive regulation of cellular component organization |
| phosphorylation |
| locomotion |
| positive regulation of developmental process |
| nervous system process |
| response to endogenous stimulus |
| intracellular transport |
| generation of neurons |
| regulation of apoptotic process |
| movement of cell or subcellular component |
| response to oxygen-containing compound |
| protein-containing complex assembly |
| regulation of programmed cell death |
| neurogenesis |
| cell development |
| regulation of cell death |
| intracellular signal transduction |
| cellular response to stress |
| positive regulation of multicellular organismal process |
| regulation of cell differentiation |
| establishment of localization in cell |
| protein-containing complex subunit organization |
| regulation of transport |
| system process |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Tissue | Fraction Of Cell Lines Where Essential |
|---|
Expression Distribution