OSBPL7
Gene Information
- Official Symbol: OSBPL7
- Official Name: oxysterol binding protein like 7
- Aliases and Previous Symbols: N/A
- Entrez ID: 114881
- UniProt: Q9BZF2
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| PH |
| Oxysterol BP |
GO Terms
| sterol transporter activity |
| sterol binding |
| cellular response to cholesterol |
| perinuclear endoplasmic reticulum |
| cellular response to sterol |
| response to cholesterol |
| bile acid biosynthetic process |
| response to sterol |
| bile acid metabolic process |
| cholesterol binding |
| sterol transport |
| autophagosome |
| cellular response to alcohol |
| positive regulation of proteasomal protein catabolic process |
| positive regulation of proteolysis involved in cellular protein catabolic process |
| steroid biosynthetic process |
| organic hydroxy compound transport |
| positive regulation of cellular protein catabolic process |
| lipid binding |
| regulation of proteasomal protein catabolic process |
| organic hydroxy compound biosynthetic process |
| monocarboxylic acid biosynthetic process |
| regulation of proteolysis involved in cellular protein catabolic process |
| positive regulation of protein catabolic process |
| response to alcohol |
| regulation of cellular protein catabolic process |
| steroid metabolic process |
| lipid transport |
| carboxylic acid biosynthetic process |
| organic acid biosynthetic process |
| lipid localization |
| regulation of autophagy |
| positive regulation of proteolysis |
| positive regulation of cellular catabolic process |
| regulation of protein catabolic process |
| positive regulation of catabolic process |
| organic hydroxy compound metabolic process |
| cellular response to lipid |
| monocarboxylic acid metabolic process |
| cellular response to organic cyclic compound |
| lipid biosynthetic process |
| small molecule biosynthetic process |
| intracellular membrane-bounded organelle |
| regulation of proteolysis |
| regulation of cellular catabolic process |
| response to lipid |
| carboxylic acid metabolic process |
| response to organic cyclic compound |
| endoplasmic reticulum membrane |
| regulation of catabolic process |
| oxoacid metabolic process |
| organic acid metabolic process |
| cellular response to oxygen-containing compound |
| lipid metabolic process |
| organic cyclic compound biosynthetic process |
| response to oxygen-containing compound |
| positive regulation of cellular protein metabolic process |
| positive regulation of protein metabolic process |
| small molecule metabolic process |
| membrane |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
| Screen | Score |
|---|---|
| Epigallocatechin gallate 20μM R05 exp230 | 1.9 |
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 5627
- Expression level (log2 read counts): 3.8
Expression Distribution
OSBPL7 Expression in NALM6 Cells: 3.8
