Pfam Domains GO Terms
| LIF OSM |
| oncostatin-M receptor binding |
| positive regulation of interleukin-17 secretion |
| oncostatin-M-mediated signaling pathway |
| regulation of interleukin-17 secretion |
| positive regulation of interleukin-17 production |
| regulation of interleukin-17 production |
| positive regulation of acute inflammatory response |
| regulation of acute inflammatory response |
| negative regulation of hormone secretion |
| positive regulation of tyrosine phosphorylation of STAT protein |
| regulation of hematopoietic stem cell differentiation |
| regulation of tyrosine phosphorylation of STAT protein |
| positive regulation of receptor signaling pathway via JAK-STAT |
| regulation of hematopoietic progenitor cell differentiation |
| positive regulation of phosphatidylinositol 3-kinase signaling |
| positive regulation of cell division |
| positive regulation of receptor signaling pathway via STAT |
| positive regulation of peptidyl-serine phosphorylation |
| regulation of stem cell differentiation |
| regulation of phosphatidylinositol 3-kinase signaling |
| regulation of receptor signaling pathway via JAK-STAT |
| regulation of receptor signaling pathway via STAT |
| regulation of peptidyl-serine phosphorylation |
| positive regulation of cytokine secretion |
| positive regulation of inflammatory response |
| growth factor activity |
| positive regulation of protein kinase B signaling |
| regulation of cell division |
| cytokine activity |
| positive regulation of peptidyl-tyrosine phosphorylation |
| negative regulation of secretion by cell |
| regulation of cytokine secretion |
| regulation of protein kinase B signaling |
| negative regulation of secretion |
| regulation of peptidyl-tyrosine phosphorylation |
| regulation of hormone secretion |
| positive regulation of protein secretion |
| positive regulation of peptide secretion |
| regulation of inflammatory response |
| positive regulation of secretion by cell |
| positive regulation of protein transport |
| positive regulation of secretion |
| positive regulation of cytokine production |
| regulation of hemopoiesis |
| positive regulation of establishment of protein localization |
| regulation of protein secretion |
| positive regulation of defense response |
| negative regulation of transport |
| regulation of peptide secretion |
| regulation of hormone levels |
| positive regulation of MAPK cascade |
| positive regulation of response to external stimulus |
| regulation of growth |
| cytokine-mediated signaling pathway |
| negative regulation of cell population proliferation |
| regulation of cytokine production |
| regulation of protein transport |
| regulation of peptide transport |
| regulation of establishment of protein localization |
| regulation of secretion by cell |
| regulation of MAPK cascade |
| regulation of defense response |
| regulation of secretion |
| positive regulation of cell population proliferation |
| positive regulation of transport |
| cellular response to cytokine stimulus |
| positive regulation of protein phosphorylation |
| positive regulation of intracellular signal transduction |
| regulation of protein localization |
| positive regulation of phosphorylation |
| regulation of response to external stimulus |
| response to cytokine |
| positive regulation of phosphorus metabolic process |
| positive regulation of phosphate metabolic process |
| positive regulation of transcription by RNA polymerase II |
| positive regulation of protein modification process |
| negative regulation of cell communication |
| negative regulation of signaling |
| regulation of protein phosphorylation |
| regulation of response to stress |
| positive regulation of transcription, DNA-templated |
| regulation of phosphorylation |
| extracellular space |
| positive regulation of cellular protein metabolic process |
| regulation of cell population proliferation |
| positive regulation of nucleic acid-templated transcription |
| positive regulation of RNA biosynthetic process |
| regulation of immune system process |
| positive regulation of signal transduction |
| positive regulation of protein metabolic process |
| positive regulation of RNA metabolic process |
| positive regulation of multicellular organismal process |
| regulation of phosphate metabolic process |
| regulation of phosphorus metabolic process |
| regulation of cell differentiation |
| positive regulation of cell communication |
| positive regulation of signaling |
| regulation of intracellular signal transduction |
| regulation of protein modification process |
| regulation of transport |
| immune response |
| positive regulation of nucleobase-containing compound metabolic process |
| positive regulation of macromolecule biosynthetic process |
| extracellular region |
| positive regulation of cellular biosynthetic process |
| positive regulation of gene expression |
| positive regulation of biosynthetic process |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution