OVGP1
Gene Information
- Official Symbol: OVGP1
- Official Name: oviductal glycoprotein 1
- Aliases and Previous Symbols: N/A
- Entrez ID: 5016
- UniProt: Q12889
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene encodes a large, carbohydrate-rich, epithelial glycoprotein with numerous O-glycosylation sites located within threonine, serine, and proline-rich tandem repeats. The gene is similar to members of the mucin and the glycosyl hydrolase 18 gene families. Regulation of expression may be estrogen-dependent. Gene expression and protein secretion occur during late follicular development through early cleavage-stage embryonic development. The protein is secreted from non-ciliated oviductal epithelial cells and associates with ovulated oocytes, blastomeres, and spermatozoan acrosomal regions. [provided by RefSeq, Jul 2008].
- UniProt Summary: Binds to oocyte zona pellucida in vivo. May play a role in the fertilization process and/or early embryonic development.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 3253
- Expression level (log2 read counts): 1.71
OVGP1 Expression in NALM6 Cells: 1.71
