PDZD11
Gene Information
- Official Symbol: PDZD11
- Official Name: PDZ domain containing 11
- Aliases and Previous Symbols: N/A
- Entrez ID: 51248
- UniProt: Q5EBL8
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| PDZ |
GO Terms
| pantothenate metabolic process |
| protein localization to basolateral plasma membrane |
| biotin metabolic process |
| maintenance of apical/basal cell polarity |
| maintenance of epithelial cell apical/basal polarity |
| pore complex |
| maintenance of cell polarity |
| pore complex assembly |
| establishment or maintenance of epithelial cell apical/basal polarity |
| establishment or maintenance of apical/basal cell polarity |
| establishment or maintenance of bipolar cell polarity |
| water-soluble vitamin metabolic process |
| presynapse |
| signal release from synapse |
| neurotransmitter secretion |
| antimicrobial humoral response |
| vitamin metabolic process |
| signal release |
| cell-cell junction |
| neurotransmitter transport |
| establishment or maintenance of cell polarity |
| basolateral plasma membrane |
| cellular modified amino acid metabolic process |
| protein localization to cell periphery |
| coenzyme metabolic process |
| synapse |
| humoral immune response |
| regulation of neurotransmitter levels |
| sulfur compound metabolic process |
| anterograde trans-synaptic signaling |
| chemical synaptic transmission |
| trans-synaptic signaling |
| cofactor metabolic process |
| synaptic signaling |
| protein localization to membrane |
| drug metabolic process |
| monocarboxylic acid metabolic process |
| cellular amide metabolic process |
| carboxylic acid metabolic process |
| ion transmembrane transport |
| oxoacid metabolic process |
| secretion by cell |
| organic acid metabolic process |
| export from cell |
| cell-cell signaling |
| secretion |
| transmembrane transport |
| response to other organism |
| response to external biotic stimulus |
| response to biotic stimulus |
| ion transport |
| protein-containing complex assembly |
| cellular protein localization |
| cellular macromolecule localization |
| small molecule metabolic process |
| establishment of localization in cell |
| protein-containing complex subunit organization |
| immune response |
| extracellular region |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
| Screen | Score |
|---|---|
| SNS-032 15μM R08 exp443 | -1.95 |
| UM131593 0.2μM R03 exp106 | 1.83 |
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/694
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/26 |
| bone | 0/26 |
| breast | 0/30 |
| central nervous system | 0/49 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/11 |
| fibroblast | 0/1 |
| gastric | 0/14 |
| kidney | 0/18 |
| liver | 0/19 |
| lung | 0/72 |
| lymphocyte | 0/16 |
| ovary | 0/25 |
| pancreas | 0/22 |
| peripheral nervous system | 0/15 |
| plasma cell | 0/12 |
| prostate | 0/1 |
| skin | 0/20 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/28 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 12048
- Expression level (log2 read counts): 3.75
Expression Distribution
PDZD11 Expression in NALM6 Cells: 3.75
