UniProt Summary: May be involved in peroxisomal proliferation and may regulate peroxisomes division (PubMed:9792670). May mediate binding of coatomer proteins to the peroxisomal membrane (By similarity). Promotes membrane protrusion and elongation on the peroxisomal surface (PubMed:20826455). {ECO:0000250|UniProtKB:O70597, ECO:0000269|PubMed:20826455, ECO:0000269|PubMed:9792670}.
Pfam DomainsGO Terms
Pfam Domains
PEX11
GO Terms
regulation of peroxisome size
peroxisome membrane biogenesis
peroxisome fission
integral component of peroxisomal membrane
brown fat cell differentiation
membrane biogenesis
peroxisomal membrane
peroxisome organization
fat cell differentiation
peroxisome
organelle fission
regulation of cellular component size
regulation of lipid metabolic process
regulation of anatomical structure size
protein-containing complex
protein homodimerization activity
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
No hits were found.
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739