UniProt Summary: Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent.
Pfam DomainsGO Terms
Pfam Domains
A1 Propeptide
Asp
GO Terms
multivesicular body lumen
aspartic-type endopeptidase activity
digestion
protein catabolic process
macromolecule catabolic process
organonitrogen compound catabolic process
proteolysis
organic substance catabolic process
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
No hits were found.
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: N/A