POU3F4
Gene Information
- Official Symbol: POU3F4
- Official Name: POU class 3 homeobox 4
- Aliases and Previous Symbols: N/A
- Entrez ID: 5456
- UniProt: P49335
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene encodes a member of the POU-III class of neural transcription factors. This family member plays a role in inner ear development. The protein is thought to be involved in the mediation of epigenetic signals which induce striatal neuron-precursor differentiation. Mutations in this gene are associated with X chromosome-linked nonsyndromic mixed deafness. [provided by RefSeq, Dec 2012].
- UniProt Summary: Probable transcription factor which exert its primary action widely during early neural development and in a very limited set of neurons in the mature brain.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 8256
- Expression level (log2 read counts): -1.45
POU3F4 Expression in NALM6 Cells: -1.45
