UniProt Summary: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity). {ECO:0000250}.
Pfam DomainsGO Terms
Pfam Domains
Pro isomerase
GO Terms
cyclosporin A binding
protein refolding
peptidyl-prolyl cis-trans isomerase activity
protein peptidyl-prolyl isomerization
peptidyl-proline modification
unfolded protein binding
protein folding
peptidyl-amino acid modification
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
No hits were found.
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739