Entrez Summary: This gene is predominantly expressed in the retina, and mutations in this gene are the cause of autosomal recessive retinal degeneration in both humans and dogs. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2010].
UniProt Summary: Involved in vision.
Pfam DomainsGO Terms
Pfam Domains
No Pfam Domain information is available for this gene.
GO Terms
photoreceptor outer segment membrane
visual perception
sensory perception of light stimulus
sensory perception
Golgi apparatus
endoplasmic reticulum
nervous system process
extracellular region
system process
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)