Entrez Summary: The protein encoded by this gene is a cytosolic prolyl endopeptidase that cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long. Prolyl endopeptidases have been reported to be involved in the maturation and degradation of peptide hormones and neuropeptides. [provided by RefSeq, Jul 2008].
UniProt Summary: Cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long.
Pfam DomainsGO Terms
Pfam Domains
Peptidase S9 N
Peptidase S9
GO Terms
serine-type exopeptidase activity
oligopeptidase activity
serine-type peptidase activity
endopeptidase activity
serine-type endopeptidase activity
proteolysis
membrane
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)