UniProt Summary: Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex. {ECO:0000250|UniProtKB:P07978}.
Pfam DomainsGO Terms
Pfam Domains
Protamine P2
GO Terms
cadmium ion binding
chromosome condensation
nucleosome
nucleus organization
spermatid development
spermatid differentiation
DNA packaging
germ cell development
DNA conformation change
cellular process involved in reproduction in multicellular organism
spermatogenesis
male gamete generation
developmental process involved in reproduction
gamete generation
multicellular organismal reproductive process
sexual reproduction
zinc ion binding
multicellular organism reproduction
multi-organism reproductive process
chromosome organization
reproductive process
reproduction
DNA binding
cell development
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)