UniProt Summary: Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex (By similarity). {ECO:0000250}.
Pfam DomainsGO Terms
Pfam Domains
No Pfam Domain information is available for this gene.
GO Terms
chromosome condensation
nucleosome
sperm motility
flagellated sperm motility
cilium or flagellum-dependent cell motility
cilium-dependent cell motility
DNA packaging
DNA conformation change
cellular component
spermatogenesis
male gamete generation
gamete generation
molecular function
multicellular organismal reproductive process
sexual reproduction
multicellular organism reproduction
multi-organism reproductive process
chromosome organization
localization of cell
cell motility
locomotion
reproductive process
reproduction
DNA binding
movement of cell or subcellular component
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)