Pfam Domains GO Terms
| Prominin |
| prominosome |
| negative regulation of caveolin-mediated endocytosis |
| microspike |
| negative regulation of pinocytosis |
| regulation of caveolin-mediated endocytosis |
| regulation of pinocytosis |
| regulation of clathrin-dependent endocytosis |
| microvillus membrane |
| negative regulation of endocytosis |
| cholesterol binding |
| ciliary membrane |
| microvillus |
| cell projection |
| regulation of receptor-mediated endocytosis |
| basolateral plasma membrane |
| cilium |
| regulation of endocytosis |
| membrane raft |
| cytoplasmic vesicle |
| apical plasma membrane |
| positive regulation of cell projection organization |
| regulation of GTPase activity |
| negative regulation of transport |
| regulation of vesicle-mediated transport |
| cell surface |
| negative regulation of cellular component organization |
| regulation of cell projection organization |
| positive regulation of protein phosphorylation |
| positive regulation of phosphorylation |
| positive regulation of phosphate metabolic process |
| positive regulation of phosphorus metabolic process |
| positive regulation of cellular component organization |
| positive regulation of protein modification process |
| regulation of hydrolase activity |
| integral component of plasma membrane |
| regulation of protein phosphorylation |
| regulation of phosphorylation |
| positive regulation of cellular protein metabolic process |
| positive regulation of protein metabolic process |
| regulation of phosphate metabolic process |
| regulation of phosphorus metabolic process |
| regulation of protein modification process |
| regulation of transport |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Screen | Score |
|---|---|
| CCT251545 20μM R07 exp326 | -1.7 |
| D-Fructose 10000μM R06 exp279 | 1.74 |
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution