RAB34
Gene Information
- Official Symbol: RAB34
- Official Name: RAB34, member RAS oncogene family
- Aliases and Previous Symbols: N/A
- Entrez ID: 83871
- UniProt: Q9BZG1"|"P0DI83|Q9BZG1"
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| Arf |
| Miro |
| Ras |
GO Terms
| phagosome-lysosome fusion |
| macropinocytosis |
| Golgi cisterna |
| pinocytosis |
| Ral GTPase binding |
| phagolysosome assembly |
| GTP-dependent protein binding |
| positive regulation of smoothened signaling pathway |
| Golgi to plasma membrane protein transport |
| Golgi stack |
| phagosome maturation |
| lysosome localization |
| establishment of protein localization to plasma membrane |
| lytic vacuole organization |
| lysosome organization |
| Golgi to plasma membrane transport |
| phagocytic vesicle |
| vesicle fusion |
| Rab protein signal transduction |
| phagocytic vesicle membrane |
| organelle membrane fusion |
| regulation of smoothened signaling pathway |
| vesicle-mediated transport to the plasma membrane |
| ruffle membrane |
| organelle fusion |
| post-Golgi vesicle-mediated transport |
| vacuole organization |
| membrane fusion |
| vesicle |
| protein localization to plasma membrane |
| cilium |
| antigen processing and presentation |
| protein localization to cell periphery |
| Ras protein signal transduction |
| establishment of protein localization to membrane |
| vesicle organization |
| small GTPase mediated signal transduction |
| phagocytosis |
| GTPase activity |
| Golgi vesicle transport |
| GTP binding |
| protein localization to membrane |
| endocytosis |
| organelle localization |
| import into cell |
| perinuclear region of cytoplasm |
| organelle assembly |
| membrane organization |
| Golgi apparatus |
| intracellular protein transport |
| cell projection organization |
| protein transport |
| intracellular transport |
| peptide transport |
| amide transport |
| cellular protein localization |
| cellular macromolecule localization |
| establishment of protein localization |
| positive regulation of signal transduction |
| intracellular signal transduction |
| positive regulation of cell communication |
| positive regulation of signaling |
| establishment of localization in cell |
| nitrogen compound transport |
| vesicle-mediated transport |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
| Screen | Score |
|---|---|
| Cadmium 60μM R08 exp462 | 1.79 |
| 5-Fluorouracil 20μM R00 exp2 | 2.02 |
Most Correlated Genes in Chemogenomics
| Gene | Correlation |
|---|---|
| GPIHBP1 | 0.401 |
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 3413
- Expression level (log2 read counts): 3.17
Expression Distribution
RAB34 Expression in NALM6 Cells: 3.17
