RAB3D
Gene Information
- Official Symbol: RAB3D
- Official Name: RAB3D, member RAS oncogene family
- Aliases and Previous Symbols: N/A
- Entrez ID: 9545
- UniProt: O95716
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: Protein transport. Probably involved in regulated exocytosis (By similarity). {ECO:0000250}.
Pfam Domains GO Terms
Pfam Domains
| Arf |
| Miro |
| Ras |
GO Terms
| secretory vesicle |
| zymogen granule |
| peptidyl-cysteine methylation |
| myosin V binding |
| GTP-dependent protein binding |
| bone resorption |
| peptidyl-cysteine modification |
| vesicle docking involved in exocytosis |
| bone remodeling |
| cytoplasmic microtubule |
| positive regulation of regulated secretory pathway |
| azurophil granule membrane |
| vesicle docking |
| exocytic process |
| Rab protein signal transduction |
| positive regulation of exocytosis |
| tissue remodeling |
| synaptic vesicle |
| protein methylation |
| protein alkylation |
| vesicle |
| protein secretion |
| establishment of protein localization to extracellular region |
| regulation of regulated secretory pathway |
| protein localization to extracellular region |
| organelle localization by membrane tethering |
| peptide secretion |
| membrane docking |
| protein localization to plasma membrane |
| tissue homeostasis |
| regulation of exocytosis |
| protein localization to cell periphery |
| Ras protein signal transduction |
| macromolecule methylation |
| endosome |
| methylation |
| small GTPase mediated signal transduction |
| multicellular organismal homeostasis |
| GTPase activity |
| anatomical structure homeostasis |
| GTP binding |
| positive regulation of secretion by cell |
| positive regulation of secretion |
| protein localization to membrane |
| neutrophil degranulation |
| neutrophil activation involved in immune response |
| neutrophil mediated immunity |
| neutrophil activation |
| granulocyte activation |
| leukocyte degranulation |
| myeloid leukocyte mediated immunity |
| myeloid cell activation involved in immune response |
| regulation of vesicle-mediated transport |
| organelle localization |
| myeloid leukocyte activation |
| leukocyte activation involved in immune response |
| cell activation involved in immune response |
| regulated exocytosis |
| regulation of secretion by cell |
| leukocyte mediated immunity |
| exocytosis |
| regulation of secretion |
| peptidyl-amino acid modification |
| leukocyte activation |
| positive regulation of transport |
| intracellular protein transport |
| secretion by cell |
| export from cell |
| cell activation |
| immune effector process |
| secretion |
| protein transport |
| intracellular transport |
| peptide transport |
| amide transport |
| cellular protein localization |
| cellular macromolecule localization |
| establishment of protein localization |
| homeostatic process |
| intracellular signal transduction |
| establishment of localization in cell |
| nitrogen compound transport |
| regulation of transport |
| immune response |
| vesicle-mediated transport |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
No hits were found.
Most Correlated Genes in Chemogenomics
| Gene | Correlation |
|---|---|
| HARS | 0.462 |
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 13647
- Expression level (log2 read counts): 2.95
Expression Distribution
RAB3D Expression in NALM6 Cells: 2.95
