RECQL4

• Official Symbol: RECQL4
• Official Name: RecQ like helicase 4
• Aliases and Previous Symbols: N/A
• Entrez ID: 9401
• UniProt: O94761
• Interactions: BioGRID
• PubMed articles: Open PubMed
• OMIM: Open OMIM

• Entrez Summary: The protein encoded by this gene is a DNA helicase that belongs to the RecQ helicase family. DNA helicases unwind double-stranded DNA into single-stranded DNAs and may modulate chromosome segregation. This gene is predominantly expressed in thymus and testis. Mutations in this gene are associated with Rothmund-Thomson, RAPADILINO and Baller-Gerold syndromes. [provided by RefSeq, Jan 2010].
• UniProt Summary: DNA-dependent ATPase. May modulate chromosome segregation. {ECO:0000269|PubMed:15317757}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

• Essentiality Rank: 1802
• Expression level (log2 read counts): 6.96

Expression Distribution

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RECQL4 Expression in NALM6 Cells: 6.96