RFPL1
Gene Information
- Official Symbol: RFPL1
- Official Name: ret finger protein like 1
- Aliases and Previous Symbols: N/A
- Entrez ID: 5988
- UniProt: O75677
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| SPRY |
| RDM |
GO Terms
| positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis |
| regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis |
| positive regulation of execution phase of apoptosis |
| negative regulation of cell division |
| regulation of execution phase of apoptosis |
| positive regulation of proteasomal ubiquitin-dependent protein catabolic process |
| negative regulation of G2/M transition of mitotic cell cycle |
| positive regulation of ubiquitin-dependent protein catabolic process |
| negative regulation of cell cycle G2/M phase transition |
| positive regulation of proteasomal protein catabolic process |
| positive regulation of proteolysis involved in cellular protein catabolic process |
| regulation of proteasomal ubiquitin-dependent protein catabolic process |
| positive regulation of cysteine-type endopeptidase activity involved in apoptotic process |
| positive regulation of cellular protein catabolic process |
| positive regulation of cysteine-type endopeptidase activity |
| regulation of ubiquitin-dependent protein catabolic process |
| regulation of cell division |
| positive regulation of endopeptidase activity |
| regulation of proteasomal protein catabolic process |
| positive regulation of peptidase activity |
| regulation of G2/M transition of mitotic cell cycle |
| regulation of cell cycle G2/M phase transition |
| negative regulation of mitotic cell cycle phase transition |
| regulation of cysteine-type endopeptidase activity involved in apoptotic process |
| regulation of proteolysis involved in cellular protein catabolic process |
| positive regulation of protein catabolic process |
| negative regulation of cell cycle phase transition |
| regulation of cysteine-type endopeptidase activity |
| regulation of cellular protein catabolic process |
| negative regulation of mitotic cell cycle |
| negative regulation of cell cycle process |
| positive regulation of proteolysis |
| positive regulation of cellular catabolic process |
| regulation of protein catabolic process |
| regulation of mitotic cell cycle phase transition |
| regulation of endopeptidase activity |
| positive regulation of catabolic process |
| regulation of peptidase activity |
| regulation of cell cycle phase transition |
| negative regulation of cell cycle |
| regulation of mitotic cell cycle |
| positive regulation of apoptotic process |
| positive regulation of programmed cell death |
| negative regulation of cell population proliferation |
| positive regulation of cell death |
| regulation of proteolysis |
| regulation of cell cycle process |
| positive regulation of hydrolase activity |
| regulation of cellular catabolic process |
| regulation of catabolic process |
| regulation of cell cycle |
| regulation of hydrolase activity |
| cell cycle |
| positive regulation of catalytic activity |
| regulation of apoptotic process |
| regulation of programmed cell death |
| positive regulation of cellular protein metabolic process |
| regulation of cell population proliferation |
| regulation of cell death |
| positive regulation of protein metabolic process |
| positive regulation of molecular function |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
No hits were found.
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 6421
- Expression level (log2 read counts): -7.68
Expression Distribution
RFPL1 Expression in NALM6 Cells: -7.68
