RGS7BP
Gene Information
- Official Symbol: RGS7BP
- Official Name: regulator of G protein signaling 7 binding protein
- Aliases and Previous Symbols: N/A
- Entrez ID: 401190
- UniProt: Q6MZT1
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: Regulator of G protein-coupled receptor (GPCR) signaling. Regulatory subunit of the R7-Gbeta5 complexes that acts by controlling the subcellular location of the R7-Gbeta5 complexes. When palmitoylated, it targets the R7-Gbeta5 complexes to the plasma membrane, leading to inhibit G protein alpha subunits. When it is unpalmitoylated, the R7-Gbeta5 complexes undergo a nuclear/cypolasmic shuttling. May also act by controlling the proteolytic stability of R7 proteins, probably by protecting them from degradation. {ECO:0000250|UniProtKB:Q8BQP9}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 15593
- Expression level (log2 read counts): -5.6
RGS7BP Expression in NALM6 Cells: -5.6
