UniProt Summary: Catalyzes the synthesis of N-acetyl-L-aspartyl-L- glutamate (NAAG) and N-acetyl-L-aspartyl-L-glutamyl-L-glutamate. {ECO:0000250|UniProtKB:Q6PFX8}.
Pfam DomainsGO Terms
Pfam Domains
GSH-S ATP
RimK
ATP-grasp 3
GO Terms
N-acetyl-L-aspartate-L-glutamate ligase activity
cellular amino acid biosynthetic process
carboxylic acid biosynthetic process
organic acid biosynthetic process
cellular amino acid metabolic process
small molecule biosynthetic process
carboxylic acid metabolic process
oxoacid metabolic process
organic acid metabolic process
organonitrogen compound biosynthetic process
ATP binding
small molecule metabolic process
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
No hits were found.
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739