RPF2

Entrez Summary: N/A
UniProt Summary: Involved in ribosomal large subunit assembly. May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus. {ECO:0000269|PubMed:24120868}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Rucaparib 6.5μM R08 exp520	-1.75

Global Fraction of Cell Lines Where Essential: 238/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	1/1
909776.0	0/1
bile duct	11/28
blood	7/28
bone	7/26
breast	8/33
central nervous system	30/56
cervix	3/4
colorectal	4/17
esophagus	5/13
fibroblast	0/1
gastric	6/16
kidney	10/21
liver	4/20
lung	18/75
lymphocyte	7/16
ovary	7/26
pancreas	9/24
peripheral nervous system	4/16
plasma cell	3/15
prostate	0/1
skin	10/24
soft tissue	5/9
thyroid	2/2
upper aerodigestive	4/22
urinary tract	7/29
uterus	2/5

Expression Distribution