RRAS2
Gene Information
- Official Symbol: RRAS2
- Official Name: RAS related 2
- Aliases and Previous Symbols: N/A
- Entrez ID: 22800
- UniProt: P62070
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene encodes a member of the R-Ras subfamily of Ras-like small GTPases. The encoded protein associates with the plasma membrane and may function as a signal transducer. This protein may play an important role in activating signal transduction pathways that control cell proliferation. Mutations in this gene are associated with the growth of certain tumors. Pseudogenes of this gene are found on chromosomes 1 and 2. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010].
- UniProt Summary: It is a plasma membrane-associated GTP-binding protein with GTPase activity. Might transduce growth inhibitory signals across the cell membrane, exerting its effect through an effector shared with the Ras proteins but in an antagonistic fashion.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 8942
- Expression level (log2 read counts): 3.83
RRAS2 Expression in NALM6 Cells: 3.83
