UniProt Summary: High affinity receptor for INSL5. Also acts as receptor for RLN3/relaxin-3, as well as bradykinin and kallidin. Binding of the ligand inhibit cAMP accumulation. {ECO:0000269|PubMed:14522967, ECO:0000269|PubMed:15525639}.
Pfam DomainsGO Terms
Pfam Domains
7tm 1
GO Terms
positive regulation of feeding behavior
galanin receptor activity
positive regulation of behavior
regulation of feeding behavior
G protein-coupled peptide receptor activity
regulation of behavior
neuropeptide signaling pathway
G protein-coupled receptor signaling pathway
integral component of plasma membrane
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
No hits were found.
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739