SEC14L2
Gene Information
- Official Symbol: SEC14L2
- Official Name: SEC14 like lipid binding 2
- Aliases and Previous Symbols: N/A
- Entrez ID: 23541
- UniProt: O76054
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: Carrier protein. Binds to some hydrophobic molecules and promotes their transfer between the different cellular sites. Binds with high affinity to alpha-tocopherol. Also binds with a weaker affinity to other tocopherols and to tocotrienols. May have a transcriptional activatory activity via its association with alpha-tocopherol. Probably recognizes and binds some squalene structure, suggesting that it may regulate cholesterol biosynthesis by increasing the transfer of squalene to a metabolic active pool in the cell.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 10566
- Expression level (log2 read counts): 2.55
SEC14L2 Expression in NALM6 Cells: 2.55
