SETBP1
Gene Information
- Official Symbol: SETBP1
- Official Name: SET binding protein 1
- Aliases and Previous Symbols: N/A
- Entrez ID: 26040
- UniProt: Q9Y6X0
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene encodes a protein which contains a several motifs including a ski homology region and a SET-binding region in addition to three nuclear localization signals. The encoded protein has been shown to bind the SET nuclear oncogene which is involved in DNA replication. Mutations in this gene are associated with Schinzel-Giedion midface retraction syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].
- UniProt Summary: N/A
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 14451
- Expression level (log2 read counts): -1.69
SETBP1 Expression in NALM6 Cells: -1.69
