SETD5
Gene Information
- Official Symbol: SETD5
- Official Name: SET domain containing 5
- Aliases and Previous Symbols: N/A
- Entrez ID: 55209
- UniProt: Q9C0A6
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This function of this gene has yet to be determined but based on sequence similarity to other SET domain proteins it may function as a histone methyltransferase. Mutations in this gene have been associated with an autosomal dominant form of intellectual disability. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2017].
- UniProt Summary: Probable transcriptional regulator that acts via the formation of large multiprotein complexes that modify and/or remodel the chromatin. Acts as a regulator of histone acetylation during gene transcription. {ECO:0000250|UniProtKB:Q5XJV7}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 7608
- Expression level (log2 read counts): 7.58
SETD5 Expression in NALM6 Cells: 7.58
