UniProt Summary: Plays an essential role in the maturation of presomitic mesoderm cells by individual attenuation of both FGF and WNT signaling. {ECO:0000250}.
Pfam DomainsGO Terms
Pfam Domains
No Pfam Domain information is available for this gene.
GO Terms
negative regulation of fibroblast growth factor receptor signaling pathway
regulation of fibroblast growth factor receptor signaling pathway
negative regulation of cellular response to growth factor stimulus
negative regulation of Wnt signaling pathway
regulation of cellular response to growth factor stimulus
regulation of Wnt signaling pathway
endoplasmic reticulum membrane
endoplasmic reticulum
negative regulation of signal transduction
negative regulation of cell communication
negative regulation of signaling
negative regulation of response to stimulus
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
No hits were found.
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739