Pfam Domains GO Terms
| Choline transpo |
| choline transmembrane transporter activity |
| choline transport |
| organic cation transport |
| phosphatidylcholine biosynthetic process |
| ammonium transport |
| phosphatidylcholine metabolic process |
| specific granule membrane |
| neurotransmitter transport |
| positive regulation of I-kappaB kinase/NF-kappaB signaling |
| ammonium ion metabolic process |
| glycerophospholipid biosynthetic process |
| glycerolipid biosynthetic process |
| regulation of I-kappaB kinase/NF-kappaB signaling |
| phospholipid biosynthetic process |
| lysosomal membrane |
| glycerophospholipid metabolic process |
| phospholipid metabolic process |
| glycerolipid metabolic process |
| neutrophil degranulation |
| neutrophil activation involved in immune response |
| neutrophil mediated immunity |
| neutrophil activation |
| granulocyte activation |
| leukocyte degranulation |
| myeloid leukocyte mediated immunity |
| myeloid cell activation involved in immune response |
| organophosphate biosynthetic process |
| lipid biosynthetic process |
| myeloid leukocyte activation |
| leukocyte activation involved in immune response |
| cell activation involved in immune response |
| regulated exocytosis |
| leukocyte mediated immunity |
| exocytosis |
| cation transport |
| organophosphate metabolic process |
| leukocyte activation |
| cellular lipid metabolic process |
| secretion by cell |
| positive regulation of intracellular signal transduction |
| export from cell |
| cell activation |
| immune effector process |
| secretion |
| lipid metabolic process |
| transmembrane transport |
| ion transport |
| organonitrogen compound biosynthetic process |
| positive regulation of signal transduction |
| positive regulation of cell communication |
| positive regulation of signaling |
| regulation of intracellular signal transduction |
| nitrogen compound transport |
| immune response |
| vesicle-mediated transport |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Screen | Score |
|---|---|
| Docetaxel 0.002μM R01 exp45 | 1.77 |
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution