UniProt Summary: Non-receptor tyrosine-protein kinase which phosphorylates DOK1 on tyrosine residues. May be involved in proliferation or differentiation of keratinocytes in the skin. {ECO:0000269|PubMed:23822091}.
Pfam DomainsGO Terms
Pfam Domains
Pkinase
Pkinase Tyr
SH2
GO Terms
peptidyl-tyrosine autophosphorylation
non-membrane spanning protein tyrosine kinase activity
extrinsic component of cytoplasmic side of plasma membrane
protein tyrosine kinase activity
peptidyl-tyrosine phosphorylation
peptidyl-tyrosine modification
protein autophosphorylation
signaling receptor binding
transmembrane receptor protein tyrosine kinase signaling pathway
enzyme linked receptor protein signaling pathway
peptidyl-amino acid modification
protein phosphorylation
negative regulation of signal transduction
phosphorylation
negative regulation of cell communication
negative regulation of signaling
ATP binding
negative regulation of response to stimulus
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)