SRRM4
Gene Information
- Official Symbol: SRRM4
- Official Name: serine/arginine repetitive matrix 4
- Aliases and Previous Symbols: N/A
- Entrez ID: 84530
- UniProt: A7MD48
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: Splicing factor specifically required for neural cell differentiation. Acts in conjunction with nPTB/PTBP2 by binding directly to its regulated target transcripts and promotes neural- specific exon inclusion in many genes that function in neural cell differentiation. Required to promote the inclusion of neural- specific exon 10 in nPTB/PTBP2, leading to increased expression of neural-specific nPTB/PTBP2. Also promotes the inclusion of exon 16 in DAAM1 in neuron extracts (By similarity). {ECO:0000250}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 14535
- Expression level (log2 read counts): 3.39
SRRM4 Expression in NALM6 Cells: 3.39
