Pfam Domains GO Terms
| Stathmin |
| negative regulation of Rac protein signal transduction |
| regulation of Rac protein signal transduction |
| microtubule depolymerization |
| hatching |
| organism emergence from protective structure |
| blastocyst hatching |
| protein depolymerization |
| microtubule polymerization or depolymerization |
| negative regulation of Ras protein signal transduction |
| cytoplasmic microtubule organization |
| tubulin binding |
| negative regulation of small GTPase mediated signal transduction |
| regulation of microtubule polymerization or depolymerization |
| blastocyst development |
| growth cone |
| cellular protein complex disassembly |
| regulation of microtubule cytoskeleton organization |
| regulation of microtubule-based process |
| protein-containing complex disassembly |
| regulation of Ras protein signal transduction |
| protein domain specific binding |
| neuron projection |
| regulation of small GTPase mediated signal transduction |
| in utero embryonic development |
| cellular component disassembly |
| supramolecular fiber organization |
| microtubule cytoskeleton organization |
| regulation of GTPase activity |
| negative regulation of intracellular signal transduction |
| regulation of cytoskeleton organization |
| chordate embryonic development |
| embryo development ending in birth or egg hatching |
| neuron projection development |
| microtubule-based process |
| neuron development |
| embryo development |
| Golgi apparatus |
| neuron differentiation |
| cytoskeleton organization |
| plasma membrane bounded cell projection organization |
| cell projection organization |
| negative regulation of signal transduction |
| regulation of hydrolase activity |
| regulation of organelle organization |
| negative regulation of cell communication |
| negative regulation of signaling |
| generation of neurons |
| negative regulation of response to stimulus |
| neurogenesis |
| cell development |
| regulation of intracellular signal transduction |
| protein-containing complex subunit organization |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Screen | Score |
|---|---|
| D-Fructose 10000μM R06 exp279 | -1.91 |
| Demecolcine 0.03μM R05 exp228 | 2.02 |
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 1/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution