SUMF1
Gene Information
- Official Symbol: SUMF1
- Official Name: sulfatase modifying factor 1
- Aliases and Previous Symbols: N/A
- Entrez ID: 285362
- UniProt: Q8NBK3
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene encodes an enzyme that catalyzes the hydrolysis of sulfate esters by oxidizing a cysteine residue in the substrate sulfatase to an active site 3-oxoalanine residue, which is also known as C-alpha-formylglycine. Mutations in this gene cause multiple sulfatase deficiency, a lysosomal storage disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009].
- UniProt Summary: N/A
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 17362
- Expression level (log2 read counts): 3.65
SUMF1 Expression in NALM6 Cells: 3.65
