Pfam Domains GO Terms
| BSD |
| TORC2 signaling |
| cellular response to insulin-like growth factor stimulus |
| positive regulation of protein homodimerization activity |
| cellular response to platelet-derived growth factor stimulus |
| response to platelet-derived growth factor |
| regulation of protein homodimerization activity |
| TOR signaling |
| cellular response to epidermal growth factor stimulus |
| response to epidermal growth factor |
| positive regulation of fat cell differentiation |
| extrinsic component of cytoplasmic side of plasma membrane |
| presynaptic membrane |
| positive regulation of protein binding |
| regulation of fat cell differentiation |
| growth cone |
| perikaryon |
| cellular response to insulin stimulus |
| positive regulation of binding |
| postsynaptic membrane |
| regulation of protein binding |
| response to insulin |
| cellular response to peptide hormone stimulus |
| axon |
| cellular response to peptide |
| positive regulation of protein serine/threonine kinase activity |
| regulation of binding |
| response to peptide hormone |
| dendrite |
| response to peptide |
| cellular response to growth factor stimulus |
| regulation of protein serine/threonine kinase activity |
| response to growth factor |
| positive regulation of protein kinase activity |
| cell junction |
| positive regulation of kinase activity |
| cellular response to organonitrogen compound |
| cellular response to hormone stimulus |
| positive regulation of transferase activity |
| cellular response to nitrogen compound |
| perinuclear region of cytoplasm |
| regulation of protein kinase activity |
| regulation of kinase activity |
| response to hormone |
| positive regulation of cell differentiation |
| regulation of transferase activity |
| Golgi apparatus |
| response to organonitrogen compound |
| positive regulation of protein phosphorylation |
| cellular response to oxygen-containing compound |
| positive regulation of phosphorylation |
| response to nitrogen compound |
| positive regulation of phosphorus metabolic process |
| positive regulation of phosphate metabolic process |
| cellular response to endogenous stimulus |
| positive regulation of protein modification process |
| positive regulation of developmental process |
| positive regulation of catalytic activity |
| regulation of protein phosphorylation |
| response to endogenous stimulus |
| response to oxygen-containing compound |
| regulation of phosphorylation |
| positive regulation of cellular protein metabolic process |
| intracellular signal transduction |
| positive regulation of protein metabolic process |
| positive regulation of molecular function |
| regulation of phosphate metabolic process |
| regulation of phosphorus metabolic process |
| regulation of cell differentiation |
| regulation of protein modification process |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Screen | Score |
|---|---|
| Disulfiram 4.3μM R06 exp281 | -1.74 |
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/26 |
| bone | 0/26 |
| breast | 0/30 |
| central nervous system | 0/49 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/11 |
| fibroblast | 0/1 |
| gastric | 0/14 |
| kidney | 0/18 |
| liver | 0/19 |
| lung | 0/72 |
| lymphocyte | 0/16 |
| ovary | 0/25 |
| pancreas | 0/22 |
| peripheral nervous system | 0/15 |
| plasma cell | 0/12 |
| prostate | 0/1 |
| skin | 0/20 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/28 |
| uterus | 0/5 |
Expression Distribution