Pfam Domains GO Terms
| regulation of synaptic activity |
| anterograde neuronal dense core vesicle transport |
| dense body |
| dense core granule localization |
| dense core granule transport |
| dense core granule cytoskeletal transport |
| secretory granule localization |
| axonal transport of mitochondrion |
| synapse maturation |
| mitochondrion transport along microtubule |
| establishment of mitochondrion localization, microtubule-mediated |
| establishment of mitochondrion localization |
| syntaxin-1 binding |
| positive regulation of insulin secretion involved in cellular response to glucose stimulus |
| kinesin binding |
| vesicle transport along microtubule |
| anterograde axonal transport |
| mitochondrion localization |
| vesicle cytoskeletal trafficking |
| axonal transport |
| regulation of insulin secretion involved in cellular response to glucose stimulus |
| axon cytoplasm |
| axo-dendritic transport |
| positive regulation of insulin secretion |
| organelle transport along microtubule |
| positive regulation of peptide hormone secretion |
| positive regulation of hormone secretion |
| vesicle |
| cytosolic transport |
| transport along microtubule |
| establishment of vesicle localization |
| cytoskeleton-dependent intracellular transport |
| regulation of insulin secretion |
| microtubule-based transport |
| vesicle localization |
| regulation of peptide hormone secretion |
| regulation of synapse structure or activity |
| microtubule binding |
| developmental maturation |
| cytoplasmic vesicle |
| regulation of hormone secretion |
| positive regulation of protein secretion |
| synapse organization |
| microtubule-based movement |
| positive regulation of peptide secretion |
| microtubule |
| establishment of organelle localization |
| positive regulation of secretion by cell |
| positive regulation of protein transport |
| positive regulation of secretion |
| modulation of chemical synaptic transmission |
| regulation of trans-synaptic signaling |
| positive regulation of establishment of protein localization |
| regulation of protein secretion |
| regulation of peptide secretion |
| regulation of hormone levels |
| organelle localization |
| Golgi membrane |
| microtubule-based process |
| intracellular membrane-bounded organelle |
| regulation of protein transport |
| regulation of peptide transport |
| regulation of establishment of protein localization |
| regulation of secretion by cell |
| regulation of secretion |
| regulation of cellular localization |
| positive regulation of transport |
| regulation of protein localization |
| intracellular transport |
| movement of cell or subcellular component |
| positive regulation of cell communication |
| positive regulation of signaling |
| establishment of localization in cell |
| regulation of transport |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution