TBL1Y

• Official Symbol: TBL1Y
• Official Name: transducin beta like 1 Y-linked
• Aliases and Previous Symbols: N/A
• Entrez ID: 90665
• UniProt: Q9BQ87
• Interactions: BioGRID
• PubMed articles: Open PubMed
• OMIM: Open OMIM

• Entrez Summary: N/A
• UniProt Summary: F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange (By similarity). {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

• Essentiality Rank: 5213
• Expression level (log2 read counts): 3.61

Expression Distribution

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TBL1Y Expression in NALM6 Cells: 3.61