Pfam Domains GO Terms
| HLH |
| respiratory system process |
| mesenchymal to epithelial transition |
| establishment of epithelial cell apical/basal polarity |
| neuromuscular process controlling posture |
| paraxial mesoderm development |
| polarized epithelial cell differentiation |
| post-anal tail morphogenesis |
| establishment of apical/basal cell polarity |
| establishment of monopolar cell polarity |
| establishment or maintenance of monopolar cell polarity |
| eating behavior |
| establishment of epithelial cell polarity |
| regulation of extracellular matrix organization |
| respiratory gaseous exchange by respiratory system |
| morphogenesis of a polarized epithelium |
| establishment or maintenance of epithelial cell apical/basal polarity |
| establishment or maintenance of apical/basal cell polarity |
| establishment or maintenance of bipolar cell polarity |
| somitogenesis |
| RNA polymerase II transcription factor complex |
| somite development |
| feeding behavior |
| muscle organ morphogenesis |
| segmentation |
| neuromuscular process |
| establishment of cell polarity |
| mesoderm development |
| protein dimerization activity |
| establishment or maintenance of cell polarity |
| anterior/posterior pattern specification |
| mesenchyme development |
| ear development |
| skeletal system morphogenesis |
| muscle organ development |
| regionalization |
| skin development |
| morphogenesis of an epithelium |
| pattern specification process |
| DNA-binding transcription activator activity, RNA polymerase II-specific |
| muscle structure development |
| skeletal system development |
| RNA polymerase II proximal promoter sequence-specific DNA binding |
| sensory organ development |
| tissue morphogenesis |
| behavior |
| chordate embryonic development |
| embryo development ending in birth or egg hatching |
| DNA-binding transcription factor activity |
| epithelial cell differentiation |
| anatomical structure formation involved in morphogenesis |
| animal organ morphogenesis |
| embryo development |
| epithelium development |
| positive regulation of transcription by RNA polymerase II |
| nervous system process |
| positive regulation of transcription, DNA-templated |
| DNA-binding transcription factor activity, RNA polymerase II-specific |
| positive regulation of nucleic acid-templated transcription |
| positive regulation of RNA biosynthetic process |
| positive regulation of RNA metabolic process |
| tissue development |
| positive regulation of nucleobase-containing compound metabolic process |
| positive regulation of macromolecule biosynthetic process |
| system process |
| positive regulation of cellular biosynthetic process |
| positive regulation of gene expression |
| positive regulation of biosynthetic process |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Screen | Score |
|---|---|
| DABN 2μM R00 exp16 | -1.78 |
| Gene | Correlation |
|---|---|
| POLR2J3 | 0.402 |
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution