UniProt Summary: May be involved in cell migration, cartilage development and in linking signal transduction pathways to the cytoskeleton (By similarity). May promote apoptosis, via its cleavage by caspase-3. {ECO:0000250}.
Pfam DomainsGO Terms
Pfam Domains
PTB
SH2
GO Terms
actin binding
cytoskeleton
focal adhesion
apoptotic process
programmed cell death
cell death
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)