Entrez Summary: This gene encodes an enzyme that hydrolyses trehalose, a disaccharide formed from two glucose molecules found mainly in fungi, plants, and insects. A partial duplication of this gene is located adjacent to this locus on chromosome 11. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014].
UniProt Summary: Intestinal trehalase is probably involved in the hydrolysis of ingested trehalose.
Pfam DomainsGO Terms
Pfam Domains
Trehalase
GO Terms
disaccharide catabolic process
alpha,alpha-trehalase activity
trehalose catabolic process
trehalose metabolic process
disaccharide metabolic process
oligosaccharide catabolic process
anchored component of plasma membrane
cellular carbohydrate catabolic process
oligosaccharide metabolic process
anchored component of membrane
carbohydrate catabolic process
cellular carbohydrate metabolic process
carbohydrate metabolic process
animal organ morphogenesis
organic substance catabolic process
cellular catabolic process
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
No hits were found.
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: N/A