TRIM15
Gene Information
- Official Symbol: TRIM15
- Official Name: tripartite motif containing 15
- Aliases and Previous Symbols: N/A
- Entrez ID: 89870
- UniProt: Q9C019
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: N/A
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| SPRY |
| zf-C3HC4 |
| zf-B box |
GO Terms
| negative regulation of intracellular transport of viral material |
| regulation of intracellular transport of viral material |
| mesodermal cell fate determination |
| positive regulation of RIG-I signaling pathway |
| mesodermal cell fate commitment |
| negative regulation of viral release from host cell |
| regulation of RIG-I signaling pathway |
| regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway |
| mesodermal cell differentiation |
| cell fate commitment involved in formation of primary germ layer |
| regulation of viral release from host cell |
| cell fate determination |
| mesoderm formation |
| mesoderm morphogenesis |
| regulation of defense response to virus |
| positive regulation of type I interferon production |
| negative regulation of viral life cycle |
| negative regulation of viral process |
| formation of primary germ layer |
| mesoderm development |
| regulation of type I interferon production |
| regulation of viral life cycle |
| positive regulation of NF-kappaB transcription factor activity |
| gastrulation |
| regulation of viral process |
| negative regulation of multi-organism process |
| positive regulation of immune effector process |
| regulation of symbiosis, encompassing mutualism through parasitism |
| cell fate commitment |
| positive regulation of DNA-binding transcription factor activity |
| negative regulation of locomotion |
| positive regulation of innate immune response |
| positive regulation of response to biotic stimulus |
| regulation of DNA-binding transcription factor activity |
| positive regulation of cytokine production |
| regulation of innate immune response |
| regulation of immune effector process |
| positive regulation of defense response |
| negative regulation of transport |
| positive regulation of multi-organism process |
| regulation of response to biotic stimulus |
| tissue morphogenesis |
| embryonic morphogenesis |
| positive regulation of response to external stimulus |
| regulation of cytokine production |
| regulation of defense response |
| innate immune response |
| regulation of multi-organism process |
| zinc ion binding |
| positive regulation of immune response |
| anatomical structure formation involved in morphogenesis |
| defense response to other organism |
| embryo development |
| regulation of locomotion |
| positive regulation of intracellular signal transduction |
| regulation of response to external stimulus |
| positive regulation of immune system process |
| regulation of immune response |
| response to other organism |
| response to external biotic stimulus |
| response to biotic stimulus |
| defense response |
| regulation of response to stress |
| positive regulation of signal transduction |
| regulation of immune system process |
| positive regulation of multicellular organismal process |
| tissue development |
| positive regulation of molecular function |
| positive regulation of cell communication |
| positive regulation of signaling |
| regulation of intracellular signal transduction |
| regulation of transport |
| immune response |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
No hits were found.
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 4275
- Expression level (log2 read counts): -2.84
Expression Distribution
TRIM15 Expression in NALM6 Cells: -2.84
