Pfam Domains GO Terms
| zf-B box |
| fn3 |
| SPRY |
| negative regulation of Ras protein signal transduction |
| negative regulation of small GTPase mediated signal transduction |
| positive regulation of ubiquitin-dependent protein catabolic process |
| positive regulation of proteolysis involved in cellular protein catabolic process |
| positive regulation of cellular protein catabolic process |
| regulation of ubiquitin-dependent protein catabolic process |
| positive regulation of protein catabolic process |
| regulation of proteolysis involved in cellular protein catabolic process |
| regulation of Ras protein signal transduction |
| regulation of cellular protein catabolic process |
| positive regulation of neuron projection development |
| regulation of small GTPase mediated signal transduction |
| positive regulation of proteolysis |
| positive regulation of cellular catabolic process |
| cytoskeleton |
| positive regulation of neuron differentiation |
| positive regulation of cell projection organization |
| regulation of protein catabolic process |
| positive regulation of catabolic process |
| positive regulation of neurogenesis |
| regulation of neuron projection development |
| negative regulation of intracellular signal transduction |
| positive regulation of nervous system development |
| regulation of cellular protein localization |
| positive regulation of cell development |
| regulation of neuron differentiation |
| regulation of plasma membrane bounded cell projection organization |
| regulation of cell projection organization |
| regulation of proteolysis |
| regulation of neurogenesis |
| regulation of cellular catabolic process |
| zinc ion binding |
| regulation of cellular localization |
| regulation of nervous system development |
| regulation of cell development |
| positive regulation of cell differentiation |
| regulation of catabolic process |
| regulation of protein localization |
| positive regulation of cellular component organization |
| negative regulation of signal transduction |
| negative regulation of cell communication |
| negative regulation of signaling |
| positive regulation of developmental process |
| generation of neurons |
| positive regulation of cellular protein metabolic process |
| negative regulation of response to stimulus |
| neurogenesis |
| positive regulation of protein metabolic process |
| positive regulation of multicellular organismal process |
| regulation of cell differentiation |
| regulation of intracellular signal transduction |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution