TRIM69
Gene Information
- Official Symbol: TRIM69
- Official Name: tripartite motif containing 69
- Aliases and Previous Symbols: N/A
- Entrez ID: 140691
- UniProt: Q86WT6
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene encodes a member of the RING-B-box-coiled-coil (RBCC) family and encodes a protein with an N-terminal RING finger motif, a PRY domain and a C-terminal SPRY domain. The mouse ortholog of this gene is specifically expressed in germ cells at the round spermatid stages during spermatogenesis and, when overexpressed, induces apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008].
- UniProt Summary: May have E3 ubiquitin-protein ligase activity. May play a role in apoptosis. {ECO:0000269|PubMed:23131556}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 3840
- Expression level (log2 read counts): 4.55
TRIM69 Expression in NALM6 Cells: 4.55
